Cavum septum pellucidum (CSP), Cavum vergae and Cavum veli interpositi

December 25, 2011 — As a single midline structure, the septum pellucidum separates the two anterior horns of the lateral ventricles. The Cavum septum pellucidum (CSP) is demarcated by the genu of the corpus callosum anteriorly , by the columns and body of the fornix posteriorly, by the body of the corpus callosum superiorly, and by the rostrum of the corpus callosum inferiorly. It consists of an ependymal lining toward the ventricles and contains neuronal and glial cell elements. These cell elements have connections to the hypothalamus and the hippocampus. At birth, the two layers of the septum pellucidum are separate and enclose a cavum. Later in life, these two layers typically fuse into a single septum. Autopsy and imaging studies have shown that all premature infants and 97% of term infants have a Cavum septum pellucidum (CSP), with the incidence dropping to 41% by 3 months of age and to 15% by 6 months of age [1,2,3,4].